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Laboratory Coordination

Chain of Custody Basics for Clinical Teams

Why specimen handling documentation matters and how teams keep it consistent.

Toxicology Management ServicesMedication monitoring management and consultingJune 26, 20265 min read

What chain of custody means

Chain of custody is the documented record of who handled a specimen and when, from collection through transport to the performing laboratory.

Where it commonly breaks

Most gaps are procedural rather than technical.

  • Incomplete labeling at the point of collection
  • Missing signatures or times during handoff
  • Undocumented storage before transport
  • Different processes at different sites

Making it routine

A short written procedure, a single form and periodic spot checks are usually enough to keep the process consistent through staff changes.

Related TMS pages

Educational content only

This article is general education for healthcare professionals and is not clinical, legal, coding or reimbursement advice. Clinical decisions remain with the treating healthcare provider. Toxicology Management Services is not a laboratory; laboratory testing is performed by qualified laboratory partners. Never submit patient information through this website.

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